The NENC Integrated Care System now has one governance procedure through the ICB Medicines Sub-Committee. This is supported by Northern Treatment Advisory Group (NTAG) and its subgroups.  Until guidance can be reviewed by the ICB Medicines Sub-Committee and its sub-groups all guidance and agreements previously approved by the predecessor three Area Prescribing Committees (APCs) of County Durham & Tees Valley; North of Tyne, Gateshead & North Cumbria; and South Tyneside & Sunderland are still valid whilst within their review date. Clinicians referring to this guidance after any expiry date should exercise caution.  ICB approved prescribing guidance and agreements will be hosted on the NTAG website moving forward and this is available publicly at .

APC guidance has been grouped according to BNF chapter.
Guidance includes
– Shared care guidance
– Clinical guidelines
– Information sheets – to help ongoing care in primary care following specialist initiation/recommendation.

Gastro-Intestinal System

Abnormal Liver Blood Test guidelines NENC Hepatology Network v3
Constipation guideline January 2023
Trans Anal Irrigation guidelines March 2023

Cardiovascular System
NENC Amiodarone shared care guideline 
Angina Guideline January 2023
Dronedarone shared care protocol – see NTAG
NEELI Clinical Guidelines – See NTAG 
North East Guideline For Use Of Sodium Glucose Co transporter 2 Inhibitors (SGLT2i) see NTAG

Respiratory System
COPD Management Guidelines v2.2 Jan 2023
Asthma – Full Guideline – Age 12+
Asthma in children – Summary Guideline January 2023

Central Nervous system
Agomelatine Primary Care Information Sheet
Dementia medicines leaflet January 2023
Adult ADHD Shared Care (extended March 2024)
Children’s ADHD Shared care June 2023
Antipsychotic Leaflet update – August 2022
Dexamfetamine-for-Narcolepsy-SCG (extended to Feb 2024)
Sativex for the treatment of spasticity in multiple sclerosis – See NTAG 
Methylphenidate Narcolepsy SCG March 2023

Regional Headache Guideline March 2022
Ketamine-in-Palliative-Care-pain-2020-v1.0 FILLABLE
Lithium-shared-care-NoTGNC-June-2022 v1.0
Methylphenidate-secondary-to-brain-injury-Sept-21 v1.0
Melatonin for the management of Sleep Wake Disorders in Children and Young People SCG amended March 2023
Melatonin Deprescribing Guideline March 2022
Vigabatrin SCG January 2023

Infections and antibiotics
Antibiotic and Diagnostic quick reference tools
Nebulised Gentamicin Information for Primary Care March 23

Endocrine System
Northern Region Gender Dysphoria Service – General Guidelines for the use of Hormone Treatment in Gender Dysphoria
NENC ICB – Management of Menopause

North East Guideline For Use Of Sodium Glucose Co transporter 2 Inhibitors (SGLT2i) – See NTAG
NENC Medication Management for Type 2 Diabetes in Adults Guidelines


Genito-Urinary System
Erectile Dysfunction Guidelines for the investigation and management of men with ED Updated August 2022
Non Surgical Management of Overactive Bladder (OAB) Pathway February 2021
Methylphenidate for giggle incontinence – Children Updated March 2023
North of Tyne, Gateshead and North Cumbria Catheter Care Product Formulary 2023

Renal Disease
Immunosuppressive-Treatment-for-Paediatric-Nephrotic-Syndrome-SCG v1.0
North-East Guideline For Use Of Sodium Glucose Co-transporter 2 Inhibitors (SGLT2i) – See NTAG

Malignant Disease and Immunosuppression
NoT G Monitoring of IMDs Updated Sept 2022
Lanreotide and Octreotide July 2019 v2.0
Immunosuppression-following-Paediatric-renal-transplantation-SCG-March 23
Tocilizumab monitoring SCG January 2023
NECN Palliative and End of life Symptom Control Guidelines 2021 (Fifth edition)

Immunosuppression following adult renal transplant

Nutrition and Blood
erythropoietin-for-CKD-SCG – January 2023
cinacalcet in primary hyperparathyroidism March 2023
NoT CMA and lactose Intolerance Guidelines March 2023
Vitamin D Quick reference guide v3.0
Gluten free guidelines Updated Nov 2022
Oral Nutritional Support guidance and formulary FINAL v1.0 Jan 2021
Faltering Growth February 2021 final

Musculoskeletal and Joint Diseases
Denosumab information sheet – Dec 2021

Ear, Eyes, Nose and Throat
Newcastle upon Tyne ENT GP Referral Guidelines
Ophthalmology Referral Guidelines January 2023


Other Guidance
Seven-day-Rx-and-MCAs v2.4
Stoma-Prescribing-Guidelines Sept 2020
Swallowing-difficulties v2.0
Third party ordering January 2023